Scientific Bases

What is DHA (docosahexaenoic acid)?

DHA (docosahexaenoic acid) is a long-chain fatty acid, 22 carbons long, 6 double bonds, and is found mainly in fish, seafood, shellfish, fish oils and some types of algae.

Main Sources of DHA

DHA is mainly found in wild fish, crustaceans and algae.

Several types of fish and their derivatives are excellent sources, and can provide a good amount per serving ( 16 ).

Among these, we have:

  • horsetail

  • Salmon (ONLY wild ones).

  • Herring.

  • Sardines.

  • Caviar.

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De Vriese SR, Christophe AB, Maes M. Lowered serum omega-3 polyunsaturated fatty acid (PUFA) levels predict the occurrence of postpartum depression: evidence that lowered n-PUFAs are related to major depression. Life Sci. 2003 Nov 7;73(25):3181-7.

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Aloe Vera / Aloe

Searching the available scientific literature, it is clear that Aloe stands out as a unique plant, with an incredible variety of health benefits. In a single plant we can find the following benefits, or aids that it provides to the organism with the purpose of:

  • Stop the growth of cancerous tumors.

  • Lower bad cholesterol levels.

  • Dissolving kidney stones and protecting against crystallization of oxalates present in coffee and some teas.

  • Alkalize the blood, which is especially useful in a world where you consume so much sugar and flour (acidifying substances).

  • Treat ulcers, irritable bowel syndrome, Crohn's disease and other digestive disorders.

  • Reduce high blood pressure by treating the cause, not just the symptoms.

  • Accelerate healing of physical and radioactive burns.

  • Replace dozens of first aid products, making the use of bandages and bactericidal sprays obsolete.

  • Help stop colon cancer by treating the intestines and lubricating the digestive tract like a balm.

  • Fix constipation.

  • Stabilize Blood Sugar Levels

  • Prevent and treat infections caused by Candida bacteria

  • Protect the liver against various diseases

  • Function as a natural isotonic, for electrolyte balance, making artificial isotonic drinks obsolete as well.

  • Increase cardiovascular performance and endurance.

  • Moisturize the skin and accelerate its regeneration in case of cuts or wounds of any kind.

  • Fluidize blood that may be too dense, thick, or sticky, making circulation much easier.

  • Increase blood oxygenation.

  • Decrease inflammatory processes and relieve arthritis pain.

  • Protect the body from oxidative stress.

All over the world, Brazil was the pioneer in banning the use of supplements that contain this plant, thus demonstrating the advance in the understanding and knowledge of our responsible authorities.

Fortunately, it is STILL possible to extract the benefits from the use of the plant itself, extracting the gel from its husk and preparing it in juices or shakes. The process itself is quick and easy, requiring only some care and attention. At the end of this article I present a practical guide with photos for homemade gel extraction.

You can easily find Aloe leaves at street markets (herb stalls), municipal markets and specialty stores.

What's in Aloe Vera Gel:

  • Water

  • 20 minerals

  • 12 vitamins

  • 18 amino acids

  • 200 active plant components (phytonutrients), including:

    • Enzymes

    • Terpenes (a phytonutrient that lowers blood sugar)

    • Glyconutrients and Glycoproteins

    • Polysaccharides, including:

      • Acemannan,

      • Mannose-6-phosphate

      • Polimannans

  • Phenolic glycosides such as Dihydrocoumarins

http://scholar.google.com/scholar?q=aloe+vera+inflammation&hl=en&lr=

http://scholar.google.com/scholar?q=aloe+vera+diabetes&hl=en&lr=

https://www.ncbi.nlm.nih.gov/pubmed/28988013

https://www.ncbi.nlm.nih.gov/pubmed/28781531

Antibacterial and antifungal activity of endodontic intracanal drugs.

CONTEXT AND OBJECTIVES:

Sterilization of the entire root system represents the main objective of every endodontist, given the control of microbial flora as a key point of each root canal treatment. The diversity of microorganisms found within the root canal and also the resistance of some bacterial species to intracanal drugs has led to a continuous development of new endodontic products. The present study focuses on comparing the antibacterial and antifungal properties of different endodontic products, two commercially available, an experimental plant-based extract and two control substances.

METHODS:

Disc diffusion assay was used to determine the antibacterial and antifungal properties of chlorhexidine, calcium hydroxide, a mixture extract between Arctium lappa root powder and Aloe barbadensis Miller gel, Amoxicillin with clavulanic acid and Fluconazole (as substances of control). Two of the most common microorganisms found in endodontic infections were chosen: Enterococcus faecalis (ATCC 29212) and Candida albicans ATCC (10231).

RESULTS:

All tested substances showed zones of inhibition around the discs, for Enterococcus faecalis and Candida albicans, including the experimental mixture extract of Arctium lappa root powder with Aloe vera gel.

CONCLUSION:

The experimental mixture extract of Arctium lappa root powder and Aloe vera gel is capable of inhibiting very resistant microorganisms, such as Enterococcus faecalis and Candida albicans.

https://www.ncbi.nlm.nih.gov/pubmed/28050502

Antibacterial effect of Aloe Vera Gel against oral pathogens: an in vitro study.

Jain S 1 , Rathod N 2 , Nagi R 3 , Sur J 4 , Laheji A 5 , Gupta N 6 , Agrawal P 7 , Prasad S 8 .

Author information

Abstract

INTRODUCTION:

Natural herbal remedies have shown promising antimicrobial properties and fewer side effects compared to synthetic antimicrobial therapy. Aloe Vera is a medicinal plant used for the management of various infections since ancient times, as it has anti-inflammatory, antimicrobial and immunological properties.

TARGET:

The aim of the present study was to determine the antimicrobial and inhibitory activities of various concentrations of Aloe Vera Gel(AVG) against oral pathogenic bacteria.

MATERIALS AND METHODS:

Submanager calcium and periapical abscess and periodontal abscess aspiration were performed in 20 patients and the sample was transferred to thioglycolate broth, which was incubated in Mutgan Sanguis agar, blood agar and cultured in an anaerobic gas chamber. The colonies formed were further identified by grass staining methods and biochemical fermentation tests (IMViC). Each isolated colony of identified bacteria was grown separately in Muller-Hilton broth and incubated at 37 °C for 24 hours. The antimicrobial activity of AVG was tested by the disk diffusion method and the minimum inhibitory concentration was determined by the broth microdilution method.

RESULT:

Various stains and biochemical tests confirmed that the sample contained Actinobacillus actinomycetemcomitans (A. actinomycetemcomitans), Clostridium bacilli (C. bacilli), Streptococcus mutans (S. mutans) and Staphlococcus aureus (Staph. Aureus). AVG showed antibacterial properties at 100% and 50% concentration ('t' value = 7,504, p-value <0.001). At lower concentration, there was no effect against the bacteria. At 100% AVG concentration, the measured zone of inhibition was 6.9 µmm in A. actinomycetemcomitans, 6.3 mm in C. bacilli, 6.8 mm in S. mutanse 6.6 mm in Staph . aureus. Standard drugs were also used to compare the antibacterial property of AVG. The result showed that a higher concentration (100%, 50%) of AVG has a zone of inhibition comparable to Ofloxacin (5mcg) and Ciprofloxacin (30mcg).

CONCLUSION:

AVG in higher concentration has shown antibacterial property and can be used as a promising adjunct to oral health care.

Turmeric

Turmeric, a root of the ginger family, is possibly one of Nature's most beneficial substances for human health. Several high-quality studies show that it delivers important results for the body and brain. Below you will see the ten evidence-proven health benefits of turmeric.

TURKEY CONTAINS BIOACTIVE COMPOUNDS WITH POTENTIAL MEDICINAL PROPERTIES

HTTPS://WWW.NCBI.NLM.NIH.GOV/PUBMED/29086882

https://www.ncbi.nlm.nih.gov/pubmed/29085611

https://www.ncbi.nlm.nih.gov/pubmed/29085504

https://www.ncbi.nlm.nih.gov/pubmed/29080451

Curcumin sensitizes lymphoma cells to DNA damaging agents through regulation of Rad51-dependent homologous recombination.

https://www.ncbi.nlm.nih.gov/pubmed/29070088

Effect of turmeric on viability, ovarian folliculogenesis, fecundity, ovarian hormones and luteinizing hormone response in rabbits.

https://www.ncbi.nlm.nih.gov/pubmed/29055920

Curcumin in hepatobiliary disease: pharmacotherapeutic properties and emerging clinical applications.

Curcumin, an aromatic phytoextract of the turmeric (Curcumalonga) rhizome, has been used for centuries for a variety of purposes, not least it is medicinal. A growing body of evidence suggests that curcumin has a wide range of potentially therapeutic pharmacological properties, including anti-inflammatory, anti-fibrotic and anti-neoplastic effects, among others. The clinical applications of curcumin have been hampered by quality control concerns and limited oral bioavailability, although new formulations appear to have largely overcome these issues. Recent in vitro and in vivo studies have found that the cytoprotective and other biological activities of curcumin may play a role in a number of benign and malignant hepatobiliary conditions, including but not limited to non-alcoholic fatty liver disease, cholestatic liver disease (eg, primary sclerosing cholangitis) and cholangiocarcinoma.

https://www.ncbi.nlm.nih.gov/pubmed/25574229

Linseed

Antioxidative and antiatherogenic effects of flaxseed, α-tocopherol and their combination in diabetic hamsters fed a high-fat diet.

Abstract

Oxidative stress has been shown to play a role in the pathogenesis of diabetes mellitus (DM) and its complications. In the present study, the effects of supplementation with dietary antioxidants, flaxseed and α-tocopherol were investigated in Syrian golden diabetic hamsters fed a high-fat diet. Thirty-five golden Syrian hamsters were randomly divided into a control group (C) and four diabetic groups (DM, DM + flax, DM + E and DM + Flax + E). Hamsters received four different diets for a period of 20 weeks, as follows: i) Groups C and DM received a diet high in fat (40% energy as fat), deficient in α-linolenic acid (ALA); ii) the flax DM +group received a high-fat diet enriched with flaxseed 15 g/100 g of foods, rich in ALA; iii) the DM + E group received a high-fat diet enriched with vitamin E, 40 mg a-tocopherol / 100 g food; and iv) DM + Flax+ Group E received a high-fat diet enriched with flaxseed and vitamin E. The results of the analysis of serum stress and oxidative stress suggested that the antiatherogenic effect of flaxseed, a-tocopherol and their combination added to a high-fat diet in diabetic hamsters was based primarily on its antioxidant role, demonstrated by decreased serum lipid peroxidation and increased liver glutathione content. Improvements in serum glucose and non-high-density lipoprotein (HDL-C) cholesterol levels were observed and may have contributed to the prevention of diabetic macroangiopathy evidenced on histopathological examination. The antioxidant effect of flaxseed was similar to that of α-tocopherol in diabetic hamsters fed a high-fat diet and combined supplementation did not appear to provide more benefit than flaxseed alone.

https://www.ncbi.nlm.nih.gov/pubmed/23571520

​​​

Flaxseed reverses atherosclerotic lesion formation and decreases lipoprotein (a) in ovarian hormone deficiency.

Campbell SC 1 , Bakhshalian N , Sadaat RL , Lerner MR , Lightfoot SA , Brackett D , Arjmandi BH .

Author information

Abstract

OBJECTIVE:

The incidence of cardiovascular disease increases dramatically during menopause and postmenopausal women seek natural alternatives to hormone therapy. Flaxseed can slow the progression of atherosclerotic lesion formation; However, it is not known whether it can reverse the formation that has already taken place.

METHODS:

Seventy-two Syrian golden hamsters were randomly divided into six groups (n = 12), operated by sham (sham) or ovariectomized (ovx) and kept on the same diet for 120 days to allow the development of the atherosclerotic lesion. After this 120-day period, whole flaxseed was introduced into hamster diets in three of the groups: group 1 (sham + casein); group 2 (ovx + casein); group 3 (ovx + 7.5% linseed); group 4 (ovx + 15% linseed); group 5 (ovx + 22.5% linseed); and group 6 (ovx + 17β-estradiol). This diet was maintained for another 120 days. Lesion regression was examined histologically and serum was analyzed for total cholesterol, triglycerides, low density lipoprotein cholesterol, high density lipoprotein cholesterol, Apo A, Apo B and lipoprotein (a).

RESULTS:

The results showed that 15% and 22.5% of flaxseed, compared to ovx animals, significantly reduced lipoprotein (a) (4.4 mg/dL [ovx] versus 2.15 mg/dL [15% of flaxseed] and 0.3 mg / dL [22.5% flaxseed]; P < 0.05) and Apo B (2.8 mg / dL [ovx] vs 2.4 mg / dL [15% flaxseed] and 2 .5 mg/dL [22.5% flaxseed]). Flax reduced the number of animals with aortic arch lesions by 67%.

CONCLUSIONS:

All three doses of flax reduce the severity of lesion formation compared to ovx controls. These results support the effectiveness of flaxseed in reducing the risk of cardiovascular disease.

https://drjulianopimentel.com.br/gluten/gluten-faz-mal-saude/

HTTPS://DRJULIANOPIMENTEL.COM.BR/ARTIGOS/DIETA-DO-OVO-EMAGRECER/

EATING AN EGG WEIGHT LOSS?

Egg contributes to weight loss as it is rich in protein.

This macronutrient slows down digestion causing the feeling of fullness to be prolonged.

Furthermore, as this digestive process takes longer, there is greater energy expenditure.

To improve, the egg has only 71 calories.

A few years ago, a survey by scientists at Louisiana State University (USA) showed that people who ate two eggs for breakfast lost 65% more weight than those who ate bread.

In addition, waist reduction was 34% greater and fat reduction, 16%.

However, it is important to emphasize that the egg diet will only contribute to weight loss if you rely on other healthy foods.

So, it is essential to invest in foods rich in fiber, vegetables, fruits, meats and reduce the consumption of processed foods, rich in sugar and saturated and trans fats.

Harms of sugar.

Apple Vinegar Really Slimming? Ask your doubts!

https://drjulianopimentel.com.br/artigos/vinagre-de-maca-emagrece/

Glutathione: The Mother of All Antioxidants - Flávio Passos

https://flaviopassos.com/2014/10/30/glutationa-a-mae-de-todos-os-antioxidantes/